... the new A-YBSlumi!
More information about the new and fast assay that determines the cumulative effect of bisphenols you can find here.
In the near future, we will present the further developed even more powerful A-YBS. By integrating the luciferase reporter gene, we have succeeded in developing a rapid (4.5 h), sustainable and sensitive assay that determines the cumulative effect of bisphenols based on the yeast Arxula adeninivorans. The A-YBSlumi is the first representative of a new yeast biosensor product line of new_diagnostics for effect-based analysis of hormonal effects.
We are in progress to adopt the ISO standardized test A-YES for the handling of low sample volumes. In particular, extracts have limited volumes and require an assay that allows the use of small sample volumes. Therefore, we are testing different well shapes in the 96 well format for the yeast cell cultivation by using the 3D print prototyping to maintain the performance of the original A-YES. The new test version for 96 well plates should replace our µA-YES in future.
The A-YMS (Arxula-Yeast Mineralcorticoid Screen) for detecting mineralcorticoid activity in water is in development. Currently the screening and stabilization of promising A. adeninivorans transformants is in progress.
Similar to our A. adeninivorans based tests, the A-YMS will be capable to detect mineralcorticoid activity in sea and brackish water, drinking or ground water as well as in wastewater and aquaeous extracts.
Our partner company QuoData provides an interlaboratory study for effect-based in vitro methods to detect estrogenic activity.