Projects

Enhancement and Optimization of Our Test Systems

November 17th, 2017|Comments Off on Enhancement and Optimization of Our Test Systems

We are determined to extend the application range of our yeast-based tests, particularly those aimed to be used for measuring endocrine disruptive effects of environmental contaminants. We are still always improving the performance of [...]

Endocrine disruption in Antarctic waters

December 14th, 2016|Comments Off on Endocrine disruption in Antarctic waters

  Chemicals that exert endocrine effects in organisms, commonly referred to as endocrine-disrupting compounds (EDCs), have become a growing concern in recent years. Exposure to EDCs is currently regarded as one of the most serious [...]

ISO standardization of the A- YES® – A standardized method for detection of estrogens in water

April 2nd, 2016|Comments Off on ISO standardization of the A- YES® – A standardized method for detection of estrogens in water

There are no limits to testing the estrogenic activity of environmental samples because there is no shortage of estrogen-like substances (ex. Bisphenol A) to investigate and no laws regulating their presence in water. This problem [...]

Development of an online-multisensor system

January 19th, 2012|Comments Off on Development of an online-multisensor system

The aim of this research project is the development of a semi-autonomous system for on-site measurement and detection of endocrine-disrupting substances in municipal wastewater treatment plants. Contamination of our water supplies with incompletely metabolized pharmaceuticals [...]

Publications

Separation and identification of hormone-active compounds using a combination of chromatographic separation and yeast-based reporter assay

November 7th, 2017|Comments Off on Separation and identification of hormone-active compounds using a combination of chromatographic separation and yeast-based reporter assay

Alexandre Chamas, Ha Thi Minh Pham, Martin Jähne, Karina Hettwer, Linda Gehrmann, JochenTuerk, Steffen Uhlig, Kirsten Simon, Kim Baronian, Gotthard Kunze Arxula adeninivorans-based yeast cell assays for the detection of steroid hormones demonstrated [...]

Submitted: Validation of Arxula Yeast Estrogen Screen assay for detection of estrogenic activity in water samples: Results of an international interlaboratory study

October 19th, 2017|Comments Off on Submitted: Validation of Arxula Yeast Estrogen Screen assay for detection of estrogenic activity in water samples: Results of an international interlaboratory study

The publication of the results of the interlaboratory trial for the development of the new ISO standard 19040-2 for the A-YES® is currently under revision. http://new-diagnostics.com/wp-content/uploads/2017/10/Orangene-Zeitung-1.jpg

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